The changes, which will affect Turns 11 to 13, are the result of enhancements to Singapore's Civic District.
The right-handed Turn 11 will remain, but will be re-aligned to sit tighter with the left-hand side of Fullerton Road, resulting in a slightly slower corner speed compared to 2014.
The left-hand Turn 12 will also be modified slightly so that drivers now enter the left lane of Anderson Bridge, before accelerating towards Turn 13 at 200km/h (124mph) - which is a similar speed to last year.
The Turn 13 hairpin meanwhile will be widened by one metre to enable more passing opportunities.
The year's race takes place September 18-20.